Ek Main Aur Ekk Tu story is set on the backdrop of Vegas and here lives Rahul (imran) who literally grows as per his parents (boman irani, ratna shah) wishes. However, he loses his job as an architect and decides to hide it from his parents till he gets another one. In this process, he comes across Riana (kareena), an independent and whacky hairstylist who is quite the opposite of Rahul. The story takes a turn when both catch up for few drinks and end up waking next morning only to realize they got married. What happens from there forms the rest of the story.