Enthiran story begins with the scientist Dr Vaseekaran (Rajinikanth) and his goal in life is to come up with a multi purpose robot that can serve the Indian army. He successfully creates one and names it Chitti (Rajinikanth). In no time, Chitti becomes a sensation and this doesn’t go well with Vaseekaran’s mentor Dr Bohra (danny). He manages to reject the robot stating it doesn’t have the power to judge and feel. Vaseekaran works on that as well but that leads to trouble to him and his lady love Sana (aishwarya). What is that trouble and where the story goes from there forms the rest.