Mayuri is set against the backdrop of a spooky forest location called ‘Mayavanam’. A lot of research is done and a movie is also made about this location which is haunted by the soul of a married woman named ‘Maya’.On the other hand, Mayuri (Nayanatara), is a single mother who works as a junior artist in Ad films. One fine day, she comes across this much talked about movie and decides to watch it.As soon as the movie begins, Mayuri gets a huge shock and finds out that the proceedings in the film have a shocking resemblance to her real life. How is Mayuri related to these incidents ? What consequences does she face after watching the film ? That forms the rest of the story.