Ramachandran (Srikanth) has a mix of positive and negative thoughts just like any other normal person in Nambiyaar. What’s exciting and new with this plot is that the negative thought Nambiyaar gets a figure in the form of Santhanam. Whenever the hero progresses to do something, the negative thought influences him and makes his life miserable. This cat and mouse game between the duo is what Nambiyaar all about. Does this game have an end? The film gives the answer with a neat message about life in the end.