Shamitabh story is about Daanish (dhanush) an aspiring hero who comes to Mumbai but he is born dumb. His passion drives him to different places only to get kicked out but one assistant director Akshara (akshara) spots Daanish’s perseverance and tries to help him. She goes in search of the perfect voice for Daanish and finds Amitabh Sinha (amitabh) a drunkard. The voice works and Daanish becomes a superstar naming himself as Shamitabh. But trouble occurs due to the ego conflict between Daanish and Amitabh. What happens from there forms the rest.