Uthama Villain starts in an ordinary fashion and with an interesting scene between Kamal Haasan and K Balachander. The story of Uthama Villain jumps between both the eras of 8th century and 21st century with different incidents on both sides.Manoranjan suffers from brain tumour and struggles hard for his life as he was in the fourth stage of tumour. Manoranjan asks his mentor KB Balachander to direct a movie for him since he has less time of lifespan.So, KB Balachander agrees to do a movie with him titled ‘Uthama Villain’. This story is about the street performance which happened in 1900.What happens to Manoranjan? What is the past life of him? Forms the rest of the story.