Manoranjan(Kamal Haasan) is a huge movie star who is loved by the masses. He leads a controversial life and hides it from his fans. One fine day, he comes to know that he has brain tumour and is going to die soon.A disappointed Manoranjan decides to make the most of his remaining time by acting in one last film. He approaches his mentor Margadarshi(K Balachander) and requests him to direct his last film. A prestigious project called Uttama Villain is launched and rest of the story is as to whether Manoranjan completes the film and fulfils his final desire.