Wake Up Sid story is set on the backdrop of Mumbai and here lives Siddarth Mehra a k a Sid (ranbir). He is a happy go lucky guy who has just graduated and believes in nothing but taking life as it comes, partying hard, go for long aimless drives and basically chill out. True to his nature, he doesn't listen much to his parents (anupam kher and supriya pathak). Sid has got two best friends in the form of Rishi (namit das) and Lakshmi (shikha) and though he has all the flaws, he is a nice guy with a good heart and an adorable nature. His life takes a turn when he chances upon Aisha Banerjee (konkona) who hails from Kolkata and arrives in Mumbai for the first time. She is focused, knows what she wants and her dream is to become a writer. Sid becomes her first friend and in no time, few situations take place which make him go for introspection. What happens from there forms the rest of the story.